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Monday, 24 August 2009 00:21

Performance Enhancing Drugs and Ergogenic Aids: A Summary of Current Literature

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PED / EA

Action

Research on Ergogenic Effects

Side Effects

Legality

Alcohol

anxiety

No benefits

Significant

Banned for shooting events

Amphetamines

Improve concentration, fatigue and appetite

Mixed, some positive

Significant, dangerous

Illegal

Anabolic steroids

strength, lean muscle mass and motivation

Positive

Significant, dangerous

Illegal

Androstenediol

Same as steroids

Limited, Refutes

Unknown

Legal

Androstenedione

Same as steroids

Refutes, no benefits

Significant

Banned by IOC, NCAA

Arginine, Ornithine, Lysine

Stimulate release of growth hormone

No benefit

None at doses used

Legal

Aspirin

pain with muscle fatigue and muscle breakdown

No benefit

Mild

Legal

Beta blockers

anxiety

Positive effect on fine motor control, negative effect on aerobic capacity

Significant

Banned by IOC

Beta2 agonists

lean muscle mass

Mixed, no benefit from inhaled formulations

Mild

Banned by IOC, legal when prescribed

Blood doping

aerobic capacity

Supports

Significant, dangerous

Illegal

Branched chain amino acids

mental fatigue

Mixed, negative

Mild at high doses

Legal

Caffeine

muscle contractility and aerobic endurance, enhances fat metabolism

Supports

Mild

Legal to urine level of 12 to 15 µg per mL

Carnitine

fat metabolism

Refutes

None

Legal

Choline

endurance

Mixed, inconclusive

None

Legal

Chromium

lean mass

Refutes, no benefit unless prior deficiency

Safe to 400 µg daily, potentially dangerous above this level

Legal

Chrysin

Inhibits aromatase, endogenous steroids

Limited, refutes

None

Legal

Coenzyme Q10 (ubiquinone)

Delays fatigue, acts as antioxidant

Refutes, no benefit

None

Legal

Creatine

muscle energy, endurance, strength and lean muscle mass

Supports, insufficient data on long-term use

Mild

Legal

DHEA

endogenous steroid production

No benefit in healthy athletes

Potentially dangerous

DHEA

Diuretics

body mass

Limited benefit

Potentially dangerous

Banned by IOC

Ephedrine

Stimulate CNS, energy, delay fatigue, stimulate weight loss

No benefit

Potentially dangerous

Ephedrine

Ephedrine plus caffeine

energy, stimulates weight loss

Supports

Potentially dangerous, fatal at high doses

Banned by IOC, some other organizations

Erythropoietin

aerobic capacity

Supports

Significant, dangerous

Illegal

GHB

Stimulates growth hormone release and muscle growth

Limited, refutes

Significant, dose-related; abuse potential

Illegal

Ginseng

endurance, enhances muscle recovery

Limited, refutes, no benefit

Mild, abuse syndrome reported

Legal

Glucosamine

An NSAID alternative, enhances recovery

Limited, may have limited NSAID abilities

None

Legal

Glutamine

Boosts immunity and growth hormone levels

May boost immunity, no other benefits

None

Legal

Glycerol

Improves hydration and endurance

Limited, supports

Mild

Legal

Guarana (herbal caffeine)

Same as caffeine

HMB

muscle breakdown, enhances recovery

Limited, some strength benefits

None

Legal

Human growth hormone

Anabolic effect on muscle growth,

Last modified on Monday, 24 August 2009 00:27